Associate Professor / Group Leader Bioinformatics
Dr. Magnus Palmblad
RESEARCH
My primary research topic is computational proteomics – ranging from experimental design to automation of and machine learning from mass spectrometry data. We pioneered the machine learning and use of predictions of peptide chromatographic behavior and isotopic distributions in proteomics - principles that are now widely incorporated in software used routinely in the field. Other ongoing work include bridging the gaps between human and model system proteomics and contextualizing omics data using a combination of text mining and computational chemistry.
Our team support collaborators at the LUMC and beyond in designing experiments and supervising staff and students, promoting robust, reusable and scalable data analysis pipelines. I play a leading role in European bioinformatics networks (ELIXIR, EuBIC), ASMS and ABRF, working to improve reproducibility of biomedical research and train the next generation of scientists in mass spectrometry, proteomics and data integration. In additional to teaching at the LUMC and within the Medical Genetics framework, I also organize international workshops on applications of machine learning in proteomics, including Lorentz Center Workshops in 2020 and 2022, and Dagstuhl Computational Proteomics Seminars 2021 and 2023.
CURRICULUM VITAE
Scientific Career History
2013 – present Associate Professor, CPM, LUMC
2007 – 2013 Assistant Professor, Biomolecular Mass Spectrometry Unit, LUMC
2005 – 2007 Senior Research Fellow, The BioCentre, The University of Reading, UK
2002 – 2005 Postdoctoral Research Associate, Center for Accelerator Mass Spectrometry, Lawrence Livermore National Laboratory, Livermore, CA, USA
1998 – 2002 Ph.D., Division of Ion Physics, Uppsala University, Uppsala, Sweden
1995 – 1996 Studies in Computer Science and Mathematics, University of Maryland College Park, MD, USA
1992 – 1998 M.Sc. Molecular Biotechnology, Uppsala University, Uppsala, Sweden
Awards and selected functions
2021 – present Topic Editor Computational Proteomics, Journal of Proteome Research
2020 – Lorentz Center Workshop on Automatic Workflow Composition in the Life Sciences, organizer
2019 – 2022 ABRF Executive Board, member, Research Group Czar
2019 & 2021 Guest Editor for Journal of Proteome Research Special Issues on Proteomics Software Tools
2018 & 2019 ASMS Mass Spectrometry Software Workshop, organizer
2017 – 2019 ASMS and HUPO Bioinformatics Hubs, organizer
2016 – present HUPO Mass Spectrometry Pillar, member
2013 – 2019 ABRF Proteome Informatics Research Group (iPRG), member/chair
2009 – 2021 Associate Editor/Senior Board Member, BMC Bioinformatics
Publications
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Theoretical Considerations for Next-Generation Proteomics
Palmblad M.
J. Proteome Res., 20(6), 3395-3399, 2021
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mzRecal: universal MS1 recalibration in mzML using identified peptides in mzIdentML as internal calibrants
Marissen R. and Palmblad M.
Bioinformatics, 37(17), 2768-2769, 2021
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A high-stringency blueprint of the human proteome
Adhikari S et al.
Nat. Commun., 11(1):5301, 2020
Groups:
Bioinformatics