About CPM

The Center for Proteomics and Metabolomics (CPM) at Leiden University Medical Center (LUMC) is the leading hub for advanced analysis of biological materials such as cells and tissues. CPM specializes in studying proteins, metabolites, lipids, and glycans, providing both innovative technologies and expert services.

Mass spectrometry is the core technology used at CPM, supported by nuclear magnetic resonance (NMR) and cutting-edge, miniaturized separation systems.

CPM is located in the main building of LUMC, on floors P0 and P1.

News

Project MERIT: Unraveling the Role of Host Metabolism in Viral Infections

May 20, 2026
Glycoproteomics investment @ LUMC

April 20, 2026
PhD thesis Mohan Ghorasaini

September 6, 2025

Groups

Proteomics

The proteomics group performs state-of-the art mass spectrometric analyses of peptides/proteins, with an historical focus on immunology, i.e. HLA-peptidomics, cell biology and microbiology.
Glycomics

Glycosylation plays important roles in immunity, development, infectious diseases and cancer.
Metabolomics

Metabolomics is defined as the systemic analysis of the metabolome, which encompasses the totality of the metabolites in a biological system, i.e., the end-points and intermediate products of metabolism
MS Imaging

Mass spectrometry imaging (MSI) is a technology that simultaneously provides the spatial distribution of hundreds of biomolecules directly from tissue.
Bioinformatics

The Bioinformatics group uses computational tools to bring together data from different domains in order to better understand human disease.
Tissue Glycomics

The Tissue Glycomics group is dedicated to study glycosylation in human tissues in health and disease.
Proteoform Profiling

Proteoforms are very diverse in structure and function. The Proteoform Profiling group focuses on developing and applying MS-based techniques to unravel the structure and function of proteoforms.