Research

The Center for Proteomics and Metabolomics (CPM) at Leiden University Medical Center (LUMC) develops advanced technologies for proteomics, glycomics, and metabolomics research. Our core expertise includes mass spectrometry, chromatography, capillary electrophoresis, and NMR.

CPM is home to seven specialized research groups and collaborates closely with academic and industry partners in biomedical and clinical research. We also provide training for bachelor, master, and PhD students, as well as visiting scientists.

Groups

Proteomics

The proteomics group performs state-of-the art mass spectrometric analyses of peptides/proteins, with an historical focus on immunology, i.e. HLA-peptidomics, cell biology and microbiology.
Glycomics

Glycosylation plays important roles in immunity, development, infectious diseases and cancer.
Metabolomics

Metabolomics is defined as the systemic analysis of the metabolome, which encompasses the totality of the metabolites in a biological system, i.e., the end-points and intermediate products of metabolism
MS Imaging

Mass spectrometry imaging (MSI) is a technology that simultaneously provides the spatial distribution of hundreds of biomolecules directly from tissue.
Bioinformatics

The Bioinformatics group uses computational tools to bring together data from different domains in order to better understand human disease.
Tissue Glycomics

The Tissue Glycomics group is dedicated to study glycosylation in human tissues in health and disease.
Proteoform Profiling

Proteoforms are very diverse in structure and function. The Proteoform Profiling group focuses on developing and applying MS-based techniques to unravel the structure and function of proteoforms.

News

Project awarded by LET'S BEAT NF

June 11, 2026
High school student visits CPM labs

May 27, 2026
Project MERIT: Unraveling the Role of Host Metabolism in Viral Infections

May 20, 2026