Dr. Tamás Pongrácz


PhD project: High-throughput glycomics and glycoproteomics

PhD thesis title: Antibody glycomics signature of SARS-CoV-2 infection and vaccination


Tamás Pongrácz obtained both his Bachelor’s degree in Medical analytics (2015) and Master’s degree in Medical Biotechnology (2017) at the University of Pécs, Hungary. In 2018, Tamas moved to the Netherlands and started to work as a PhD candidate and Marie Curie Fellow at Leiden University Medical Center in the department of Center for Proteomics and Metabolomics under the supervision of Prof. Dr. Manfred Wuhrer and Dr. Noortje de Haan. As part of his PhD, he was involved in a multidisciplinary and intersectoral research training program IMforFUTURE within the frames of Horizon 2020 Marie Skłodowska-Curie Actions. His projects focused on high-throughput clinical glycomics in various disease settings, such as autoimmune hepatitis, transplantation and COVID-19, as well as mechanistic studies in the field of linkage-specific sialic acid derivatization. Tamas defended his PhD thesis in September 2022 and currently works as a postdoctoral researcher at the Center  for Proteomics and Metabolomics.


  • Immunoglobulin G1 Fc glycosylation as an early hallmark of severe COVID-19

    Pongracz, Tamas; Nouta, Jan; Wang, Wenjun; van Meijgaarden, Krista E.; Linty, Federica; Vidarsson, Gestur; Joosten, Simone A.; Ottenhoff, Tom H. M.; Hokke, Cornelis H.; de Vries, Jutte J. C.; Arbous, Sesmu M.; Roukens, Anna H. E.; Wuhrer, Manfred

    eBioMedicine, 2022, 78, 103957, DOI: 10.1016/j.ebiom.2022.103957

  • Afucosylation of HLA-specific IgG1 as a potential predictor of antibody pathogenicity in kidney transplantation

    Bharadwaj, Pranay†; Shrestha, Sweta†; Pongracz, Tamas†; Concetta, Catalano†; Sharma, Shilpee; Le Moine, Alain; de Haan, Noortje; Murakami, Naoka; Riella, Leonardo V.; Holovska, Vanda; Wuhrer, Manfred; Marchant, Arnaud; Ackerman, Margaret E.

    Cell Reports Medicine, 2022, 3 (11), pages, DOI:

  • Expanding the reaction space of linkage-specific sialic acid derivatization

    Pongracz, Tamas; Wuhrer, Manfred; de Haan, Noortje

    Molecules, 2019, 24 (19), 3617, DOI: 10.3390/molecules24193617

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