Assistant Professor / Group leader Tissue Glycomics
Dr. Noortje de Haan
DETAILS
I am a glycoscientist at the Center for Proteomics and Metabolomics at the Leiden University Medical Center, The Netherlands. Additionally, I am affiliated with the Copenhagen Center for Glycomics at the University of Copenhagen in Denmark. My research focus is on mass spectrometric method development for glycomics and glycoproteomics, with special interest in tissue glycomics and clinical translation.
In 2019, I received my PhD at the Leiden University Medical Center, on the development and application of mass spectrometry-based methods for the analysis of (antibody) glycosylation. Subsequently, I started a postdoc at the Copenhagen Center for Glycomics where I work with glycogenomics, 3D tissue models and advanced mass spectrometry for glycomics and glycoproteomics.
CURRICULUM VITAE
2023-present: Assistant professor the Center for Proteomics and Metabolomics, Leiden University Medical Center, The Netherlands.
2023-present: Visiting researcher at the Copenhagen Center for Glycomics, University of Copenhagen, Denmark.
2020-2023: Postdoctoral researcher at the Copenhagen Center for Glycomics, University of Copenhagen, Denmark.
2022-2023: Visiting researcher at the Center for Proteomics and Metabolomics, Leiden University Medical Center, The Netherlands.
2020-present: Member of the European Glycoscience Community, co-organizing and hosting the analytical glycoscience sessions of the bimonthly webinar series.
2018-2020: Postdoctoral researcher at the Leiden University Medical Center, Center for Proteomics and Metabolomics, Leiden, The Netherlands.
2014-2018 PhD-student at the Leiden University Medical Center, Center for Proteomics and Metabolomics, Leiden, The Netherlands. Thesis: Clinical Glycomics of Antibodies by Mass Spectrometry (cum laude)
2012-2014 Master program Biomarkers and Clinical Chemical Analysis at the VU university, Amsterdam, The Netherlands
2012-2014 MSc+ Program Analytical Chemistry, at TI-COAST, Amsterdam, The Netherlands
2009-2012 Bachelor program Pharmaceutical Sciences at the VU university, Amsterdam, The Netherlands
Publications
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Global mapping of GalNAc-T isoform-specificities and O-glycosylation site-occupancy in a tissue-forming human cell line.
M Nielsen*, N de Haan*, W Kightlinger, Z Ye, S Dabelsteen, M Li, M Jewett, I Bagdonaite, S Vakhrushev, HH Wandall * Equal contributing authors
Nature Communications, 2022, in press.
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In-Depth Profiling of O-Glycan Isomers in Human Cells Using C18 Nanoliquid Chromatography–Mass Spectrometry and Glycogenomics
N de Haan, Y Narimatsu, M Koed Møller Aasted, ISB Larsen, IN Marinova, S Dabelsteen, SY Vakhrushev, HH Wandall
Analytical Chemistry, 2022, 94 (10) 4343-4351.
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Semiautomated glycoproteomics data analysis workflow for maximized glycopeptide identification and reliable quantification.
S Lippold, AH de Ru, J Nouta, PA van Veelen, M Palmblad, M Wuhrer, N de Haan
Beilstein J. Org. Chem., 2020, 16 (1), 3038-3051.
Groups:
Tissue Glycomics
