EU Mission on Cancer Grant for Spatial Omics in Lung Cancer Research

August 22, 2024

Researchers at the Center for Proteomics and Metabolomics (CPM) have been awarded €381,042 to map the molecular composition of lung cancer tissue. This research is part of the EU Mission on Cancer SPACETIME project, led by Amsterdam UMC and involving 15 partners from 7 countries, aimed at studying the microenvironment of lung cancer cells and improving lung cancer treatment. At CPM, the latest advancements in mass spectrometry imaging will be used to study the metabolome, lipidome, and glycome of lung cancer. The CPM SPACETIME team includes dr. Noortje de Haan, dr. Nina Ogrinc, dr. Elena Sánchez López, and Rick Ursem.

EU Mission on Cancer Grant for Spatial Omics in Lung Cancer Research

Groups

Proteomics

The proteomics group performs state-of-the art mass spectrometric analyses of peptides/proteins, with an historical focus on immunology, i.e. HLA-peptidomics, cell biology and microbiology.
Glycomics

Glycosylation plays important roles in immunity, development, infectious diseases and cancer.
Metabolomics

Metabolomics is defined as the systemic analysis of the metabolome, which encompasses the totality of the metabolites in a biological system, i.e., the end-points and intermediate products of metabolism
MS Imaging

Mass spectrometry imaging (MSI) is a technology that simultaneously provides the spatial distribution of hundreds of biomolecules directly from tissue.
Bioinformatics

The Bioinformatics group uses computational tools to bring together data from different domains in order to better understand human disease.
Tissue Glycomics

The Tissue Glycomics group is dedicated to study glycosylation in human tissues in health and disease.
Proteoform Profiling